Portfolio

A Portfolio Diversified Across Partners, Indications, Technologies and Stage of Development

Ligand has assembled one of the largest portfolios of biopharmaceutical assets among our peers which provides investors the opportunity to participate in the promise of the biotech industry in a profitable, diversified and lower-risk business than a typical biotech company.

Program Partner Indication Technology Development Stage
Preclinical Phase 1 Phase 2 Phase 3 NDA Marketed
VFEND Pfizer Infectious Disease Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA Complete
Marketed In Progress
Noxafil-IV Merck Infectious Disease Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA Complete
Marketed In Progress
Carnexiv Lundbeck CNS Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA Complete
Marketed In Progress
Interferon beta-1a Biocad Inflammation/Metabolic Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA Complete
Marketed In Progress
Promacta Novartis Blood Disorders Other
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA Complete
Marketed In Progress
Vivitra Zydus Cadila Inflammation/Metabolic Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA Complete
Marketed In Progress
Nexterone Baxter Cardiovascular Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA Complete
Marketed In Progress
Exemptia Zydus Cadila Inflammation/Metabolic Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA Complete
Marketed In Progress
Kyprolis Amgen Cancer Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA Complete
Marketed In Progress
Duavee Pfizer Inflammation/Metabolic Other
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA Complete
Marketed In Progress
EVOMELA Spectrum Cancer Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA Complete
Marketed In Progress
Voriconazole Alvogen Infectious Disease Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA Complete
Marketed In Progress
Viviant/Conbriza Pfizer Inflammation/Metabolic Other
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA Complete
Marketed In Progress
Baxdela Melinta Infectious Disease Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA In Progress
Marketed Not Started
CE-Fosphenytoin Sedor CNS Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 Complete
NDA In Progress
Marketed Not Started
Brexanolone (SAGE-547) SAGE CNS Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 In Progress
NDA Not Started
Marketed Not Started
CS-3150 Exelixis / Daiichi-Sankyo Cardiovascular Other
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 In Progress
NDA Not Started
Marketed Not Started
BCD-066 Biocad Blood Disorders Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 In Progress
NDA Not Started
Marketed Not Started
ONS-1045 Oncobiologics Cancer Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 In Progress
NDA Not Started
Marketed Not Started
Promacta (MDS/AML) Novartis Cancer Other
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 In Progress
NDA Not Started
Marketed Not Started
ONS-3010 Oncobiologics Cancer Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 In Progress
NDA Not Started
Marketed Not Started
Verubecestat Merck CNS Other
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 In Progress
NDA Not Started
Marketed Not Started
CHS-0214 Coherus Inflammation/Metabolic Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 In Progress
NDA Not Started
Marketed Not Started
ADX-102 (NS-2) Aldeyra Other/Undisclosed Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
TR Beta Viking Inflammation/Metabolic Other
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
VK5211 Viking Inflammation/Metabolic Other
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
SAR125844 Sanofi Cancer Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
BMS986231 (CXL-1427) Cardioxyl / BMS Cardiovascular Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
BAX-69 Baxter Cancer Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Lubricin Lubris Inflammation/Metabolic Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
hCDR1 XTL Bio Severe and Rare Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OPT-302 Opthea Other/Undisclosed Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
VX-970 Merck KGaA Cancer Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Aplindore Seelos Therapeutics CNS Other
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
VK0612 Viking Inflammation/Metabolic Other
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
MLN-4924 Millennium / Takeda Cancer Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Prexasertib (LY2606368) Eli Lilly Cancer Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Sparsentan Retrophin Severe and Rare Other
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
MM-141 Merrimack Cancer Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
KLM465 ('5921) Novartis Blood Disorders Other
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
VTX-2337 VentiRx Cancer Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
NPC-1C Precision Biologics Cancer Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Lasofoxifene Sermonix Inflammation/Metabolic Other
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
MM-121 Merrimack Cancer Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Promacta (CIT) Novartis Blood Disorders Other
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
ODSH Cantex Cancer Other
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 Not Started
NDA Not Started
Marketed Not Started
TAK-020 Takeda Inflammation/Metabolic Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
GNR-008 IBC Generium Severe and Rare Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
F-102 F-Star Cancer Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
UC-961 ROAR Therapeutics Cancer Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Altiratinib Deciphera Cancer Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Deplera IBC Generium Cancer Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Merestinib Eli Lilly Cancer Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
LY3023703 Eli Lilly CNS Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
MB07133 Chiva Cancer Other
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
AMG-330 Amgen Cancer Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Trametinib Novartis Cancer Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
CXCR4 Upsher Smith Cancer Other
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
GS-5734 Gilead Infectious Disease Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Pradefovir Chiva Infectious Disease Other
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
ME-143 MEI Cancer Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
ME-344 MEI Cancer Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
CE-Budesonide Sedor Inflammation/Metabolic Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
IV Topiramate CURx CNS Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Trastuzumab Gedeon Richter Cancer Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OPC-269 Otsuka Cardiovascular Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
EPOR Agonist Biocad Blood Disorders Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
VTX-1463 VentiRx Cancer Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Bevacizumab Gedeon Richter Cancer Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
RGB-03 Gedeon Richter Inflammation/Metabolic Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
XL652 Exelixis / Daiichi-Sankyo Cardiovascular Other
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
MM-151 Merrimack Cancer Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Seattle Genetics Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Symphogen Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb WuXi Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Stemcentrx / AbbVie Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Janssen Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Teneobio Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Gilead Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Hanall Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Merck KGaA Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Pfizer Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
NUC-101 Nucorion Infectious Disease Other
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
NUC-202 Nucorion Infectious Disease Other
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
NUC-404 Nucorion Cancer Other
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
H3 Receptor Antagonist Seelos Therapeutics Inflammation/Metabolic Other
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
CE programs Avion Other/Undisclosed Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Genmab Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
LRP-6 Merck KGaA Cancer OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Tizona Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
PDL-1 antibody C-Stone Cancer OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
PD-1 antibody Gloria Cancer OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
FGFR1 Merck KGaA Cancer OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Teva Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb ABBA Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
LTP-O3FA Omthera / AstraZeneca Inflammation/Metabolic Other
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
IRAK4 TG Therapeutics Cancer Other
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Ganaxalone IV Marinus CNS Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
CE-Propofol Cuda CNS Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
SAGE-689 SAGE CNS Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Lasofoxifene Azure Inflammation/Metabolic Other
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
EPOR Agonist Viking Blood Disorders Other
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
DGAT-1 Inhibitor Viking Inflammation/Metabolic Other
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
CE-Meloxicam Sedor Inflammation/Metabolic Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
ML-061 Meridian Cancer Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
IV Lamotrigine CURx CNS Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Cantrixil Novogen Cancer Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb ARMO Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Celgene Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Aptevo Therapeutics Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb F-Star Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Amgen Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
CE - Cannibinoids Vireo Health Inflammation/Metabolic Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Rituximab Oncobiologics Cancer Selexis SUREtechnology
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
ONS-1050 Oncobiologics Cancer Selexis SUREtechnology
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
Undisclosed AiCuris Infectious Disease Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started
OmniAb Five Prime Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 Not Started
NDA Not Started
Marketed Not Started