Press Releases

Ligand to Hold Third Quarter Results Conference Call on November 6

SAN DIEGO--

Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) announced today that it plans to report third quarter 2008 financial results on Thursday, November 6, 2008, following the close of market. Ligand's President and CEO, John L. Higgins and Vice President of Finance and CFO, John Sharp will host the conference call.

What:            Ligand Pharmaceuticals conference call to discuss
                  financial results and provide general business
                  updates.

When:            Thursday, November 6, 2008

Time:            1:30 p.m. Pacific time (4:30 p.m. Eastern time)

Webcast:         Conference call and replay accessible at
                  www.ligand.com.

Conference Call: (877) 356-5578, ID # 68990993 (U.S.)
                 (706) 679-0565, ID # 68990993 (outside the U.S)

Replay:          (800) 642-1687, ID # 68990993 (U.S.)
                 (706) 645-9291, ID # 68990993 (outside the U.S.)
                 Replay of conference call will be available from
                  November 6, 2008 to December 6, 2008.

About Ligand Pharmaceuticals

Ligand discovers and develops new drugs that address critical unmet medical needs of patients in the areas of thrombocytopenia, hepatitis C, cancer, hormone-related diseases, osteoporosis and inflammatory diseases. Ligand's proprietary drug discovery and development programs are based on its leadership position in gene transcription technology.

Source: Ligand Pharmaceuticals Incorporated