Portfolio

A Portfolio Diversified Across Partners, Indications, Technologies and Stage of Development

Ligand has assembled one of the largest portfolios of biopharmaceutical assets among our peers which provides investors the opportunity to participate in the promise of the biotech industry in a profitable, diversified and lower-risk business than a typical biotech company.

Program Partner Indication Technology Development Stage
Preclinical Phase 1 Phase 2 Phase 3 or Regulatory Approved
Carnexiv Lundbeck CNS Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Vfend-IV Pfizer Infectious Disease Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Posaconazole Par Pharmaceuticals Infectious Disease Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Aziyo Base Business Aziyo Medical Device Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Cangaroo Envelope Aziyo Medical Device Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Promacta Novartis Blood Disorders Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Duavee Pfizer Inflammatory/Metabolic Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Viviant/Conbriza Pfizer Inflammatory/Metabolic Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Baxdela Melinta Infectious Disease Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Exemptia Zydus Cadila Inflammatory/Metabolic Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Bryxta Zydus Cadila Oncology Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Evomela Spectrum Oncology Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Kyprolis Amgen Oncology Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Voriconazole Hikma Infectious Disease Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Voriconazole Alvogen Infectious Disease Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Noxafil-IV Merck Infectious Disease Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Vivitra Zydus Cadila Oncology Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
Nexterone Baxter Cardiovascular Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory Complete
Approved In Progress
CHS-0214 Coherus Inflammatory/Metabolic Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory In Progress
Approved Not Started
CE-Fosphenytoin Sedor CNS Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory In Progress
Approved Not Started
Brexanolone SAGE CNS Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory In Progress
Approved Not Started
Pevonedistat Takeda Oncology Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory In Progress
Approved Not Started
BCD-066 Biocad Blood Disorders Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory In Progress
Approved Not Started
CS-3150 Exelixis/Daiichi-Sankyo Cardiovascular Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory In Progress
Approved Not Started
ONS-3010 Oncobiologics Oncology Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory In Progress
Approved Not Started
ONS-1045 Oncobiologics Oncology Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 Complete
Phase 3 or Regulatory In Progress
Approved Not Started
MM-141 Merrimack Pharma Oncology Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
Reproxalap Aldeyra Therapeutics Other/Undisclosed Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
Lasofoxifene Sermonix Inflammatory/Metabolic Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
OPT-302 Opthea Ltd Other/Undisclosed Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
MM-121 Merrimack Pharma Oncology Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
Ganaxalone IV Marinus Pharma CNS Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
GS-5734 Gilead Infectious Disease Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
Aplindore Seelos CNS Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
Ensituximab Precision Biologics Oncology Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
Lubricin Novartis Oncology Selexis SUREtechnology
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
VK5211 Viking Inflammatory/Metabolic Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
VTX-2337 VentiRx Pharma Oncology Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
VK0612 Viking Inflammatory/Metabolic Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
hCDR1 XTL Bio Cardiovascular Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
KLM465 Novartis Blood Disorders Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
Merestinib Eli Lilly Oncology Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
TR Beta Viking Inflammatory/Metabolic Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
Prexasertib Eli Lilly Oncology Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
Sparsentan Retrophin Cardiovascular Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
BMS986231 BMS Cardiovascular Captisol
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
RVT-1502 Roivant Inflammatory/Metabolic Other/NCE
Preclinical Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3 or Regulatory Not Started
Approved Not Started
OPC-108459 Otsuka Cardiovascular Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
GNR-008 IBC Generium Cardiovascular Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
Pradefovir Chiva Pharma Infectious Disease Other/NCE
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
Cudafol Cuda Pharma CNS Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
CXCR4 Upsher-Smith Oncology Other/NCE
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
TAK-020 Takeda Inflammatory/Metabolic Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
Mekinist POS Novartis Oncology Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
anti-FcRN Hanall Inflammatory/Metabolic OmniAb
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
PCSK-9 Genekey Biotech Inflammatory/Metabolic OmniAb
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
RGB-03 Gedeon Richter Inflammatory/Metabolic Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
IV Topiramate CURx Pharma CNS Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
VTX-1463 VentiRx Pharma Oncology Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
F-102 F-Star Oncology Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
MB07133 Chiva Pharma Oncology Other/NCE
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
AMG-330 Amgen Oncology Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
ML-061 Meridian Oncology Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
Trastuzumab Gedeon Richter Oncology Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
PDL-1 C-Stone Oncology OmniAb
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
PD-1 Gloria Oncology OmniAb
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
BCMAxCD3 Janssen Oncology OmniAb
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
JPH-203 (Injection) J-Pharma Oncology Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
Deplera IBC Generium Oncology Selexis SUREtechnology
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
ME-344 MEI Pharma Oncology Captisol
Preclinical Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
IRAK4 TG Therapeutics Oncology Other/NCE
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
Lasofoxifene Azure Inflammatory/Metabolic Other/NCE
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
anti-FcRN Roivant Inflammatory/Metabolic OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
CE-Meloxicam Sedor Inflammatory/Metabolic Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
LTP-O3FA Omthera/AstraZeneca Inflammatory/Metabolic Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
anti-FcRN Harbour Inflammatory/Metabolic OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Tetragenics Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
CE-Budesonide Sedor Inflammatory/Metabolic Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Teva Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Tizona Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb WuXi Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb xCella Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
NUC-101 Nucorion Infectious Disease Other/NCE
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
SAGE-689 SAGE CNS Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
IV Lamotrigine CURx Pharma CNS Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
CE-Acetaminophen Seelos CNS Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
PD-1 Arcus Oncology OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
EPOR Agonist Viking Blood Disorders Other/NCE
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
CE-Ziprasodone Beloteca CNS Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
NUC-202 Nucorion Infectious Disease Other/NCE
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
DGAT-1 Inhibitor Viking Inflammatory/Metabolic Other/NCE
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
H3 Receptor Antagonist Seelos Inflammatory/Metabolic Other/NCE
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
CE-Cannabinoids Vireo Health Inflammatory/Metabolic Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
Undisclosed AiCuris GmBH Infectious Disease Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Teneobio Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
CRTH2 Antagonist Seelos Inflammatory/Metabolic Other/NCE
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Merck KGaA Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
CE programs Avion Other/Undisclosed Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb ARMO Biosciences Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Bluebird Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Boehringer Ingelheim Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Celgene Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Aptevo Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Amgen Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb ABBA Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb AbbVie Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Achaogen Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Alexo Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Ferring Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Five Prime Therapeutics Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Ono Pharmaceuticals Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Janssen Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Pfizer Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Seattle Genetics Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Surface Oncology Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
CE-program Interventional Analgesix Other/Undisclosed Captisol
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Hanall Biopharma Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb F-Star Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Genmab Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Gilead Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Glenmark Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started
OmniAb Symphogen Other/Undisclosed OmniAb
Preclinical In Progress
Phase 1 Not Started
Phase 2 Not Started
Phase 3 or Regulatory Not Started
Approved Not Started