Portfolio

A Portfolio Diversified Across Partners, Indications, Technologies and Stage of Development

Ligand has assembled one of the largest portfolios of biopharmaceutical assets among our peers which provides investors the opportunity to participate in the promise of the biotech industry in a profitable, diversified and lower-risk business than a typical biotech company.

Partner Program Technology Indication Development Stage
Pre-clinical/IND Phase 1 Phase 2 Phase 3/NDA Approved
Acrotech/CASI Evomela Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Alvogen Voriconazole Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Amgen/Ono Kyprolis Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Aytu Bioscience Tuzistra Vernalis Design Platform Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Aziyo ECM portfolio ECM Med Device/Cardiology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Baxter Nexterone Captisol Cardiovascular Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Biocad Teberif Selexis SUREtechnology Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Exelixis/Daiichi-Sankyo Minnebro Other/NCE Metabolic Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Hikma Pharmaceuticals Voriconazole (EU) Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Lundbeck Carnexiv Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Melinta Baxdela Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Menarini Frovatriptan Vernalis Design Platform Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Merck Noxafil IV Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Nanjing King-Friend Voriconazole (China and US) Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Par Pharmaceuticals Posaconazole-Par Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Pfizer Duavee Other/NCE Women's Health
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Pfizer VFEND Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Pfizer Viviant/Conbriza Other/NCE Women's Health
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Sage Zulresso Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Zydus Bryxta and Zybev Selexis SUREtechnology Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Zydus Exemptia Selexis SUREtechnology Inflammatory Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Zydus Rituximab Selexis SUREtechnology Inflammatory Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Zydus Vivitra Selexis SUREtechnology Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Zydus Vortuxi Selexis SUREtechnology Inflammatory Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Aldeyra Reproxalap Captisol Ophthalmology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Aytu Bioscience CCP-07/08 Vernalis Design Platform Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Biocad BCD-066 (Darbopoeitin) Selexis SUREtechnology Hematology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
CStone CS1001 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
IBC Generium GNR-008 (Imiglugerase biosimilar) Selexis SUREtechnology Genetic Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Medivis CE-Opthalmology Captisol Ophthalmology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Outlook Therapeutics ONS-3010 Selexis SUREtechnology Inflammatory Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Outlook Therapeutics ONS-5010 Selexis SUREtechnology Ophthalmology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Palvella Therapeutics PTX-022 Other/NCE To Be Determined
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Pharmascience Voriconazole (Canada) Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Retrophin Sparsentan Other/NCE Metabolic Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Sanofi Sutimlimab Selexis SUREtechnology Autoimmune
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Sedor CE-Fosphenytoin Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Sunshine Lake Pharma Vilazodone Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Takeda Pevonedistat (TAK-924) Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Arcus Zimberelimab OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Cardioxyl/BMS Cimlanod Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Corvus Ciforadenant and Atezolizumab Vernalis Design Platform Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Corvus Ciforadenant Vernalis Design Platform Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
CTI BioPharma CHR2797 (Tosedostat) Vernalis Design Platform Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Eisai FYCOMPA (Perampanel) Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Gilead Remdesivir Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Gloria GLS-010 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
HanAll Biopharma/Harbour BioMed Batoclimab (HL161/HBM9161), (Korea/China) OmniAb Autoimmune
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Immunovant IMVT-1401 (WW – Ex China/Korea) OmniAb Immunology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
J-Pharma JPH203-SBECD Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Marinus Ganaxalone-IV Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Merck KGaA M6620 Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Novartis ECF843 (Lubricin) Selexis SUREtechnology Ophthalmology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Novartis CE-Trametinib Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Opthea OPT-302 Selexis SUREtechnology Ophthalmology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Precision Biologics NEO-102 (Ensituximab) Selexis SUREtechnology Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Sedor CE-Budesonide Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Seelos SLS-006 Other/NCE Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Sermonix Lasofoxifene Other/NCE Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
VentiRx Motolimod (VTX-2337) Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Verona Ensifentrine Vernalis Design Platform Respiratory Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Viking VK-0612 Other/NCE Metabolic Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Viking VK-5211 Other/NCE Musculoskeletal Disorder
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Viking VK-2809 HepDirect Metabolic Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Xi'an Xintong Pradefovir HepDirect Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
XTL hCDR1 Captisol Inflammatory Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Amgen AMG-330 Captisol Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Aptevo APVO436 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Corvus Ciforadenant Vernalis Design Platform Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
CSL CSL-324 Selexis SUREtechnology Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Cuda Cudafol Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
F-Star FS-102 Selexis SUREtechnology Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Gedeon Richter Bevacizumab biosimilar Selexis SUREtechnology Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Gedeon Richter RGB-03 (Rituximab biosimilar) Selexis SUREtechnology Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Genekey Biotech Anti-PCSK-9 OmniAb Metabolic Disease
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
GenMab GEN1046-(PD-L1x4-1BB) OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Gossamer Bio PFK-158 Captisol Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Janssen JNJ-64007957 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Janssen JNJ-67371244 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
MEI ME-344 Captisol Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Meridian ML-061 Captisol Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Neuritek NCO-48 Fumarate (NCO-1010) LTP Platform HBV
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Novartis S55746 (BCL-201) Vernalis Design Platform Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Novartis MIK-665 (S64315) Vernalis Design Platform Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Phoenix Tissue Repair PTR-01 Selexis SUREtechnology Genetic Disease
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Proximagen USL311 Other/NCE Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Servier S55746/S64315 Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Symphogen SYM022 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Symphogen SYM023 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Takeda TAK-925 Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Teva Anti-IL5 OmniAb TBD
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Vaxxas Nanopatch Captisol To Be Determined
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
VentiRx VTX-1463 Captisol Inflammatory Disease
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Xi'an Xintong MB07133 HepDirect Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started


Ligand’s partners currently have over 100 drug candidates in discovery/pre-clinical development or an IND has been filed