Portfolio

A Portfolio Diversified Across Partners, Indications, Technologies and Stage of Development

Ligand has assembled one of the largest portfolios of biopharmaceutical assets among our peers which provides investors the opportunity to participate in the promise of the biotech industry in a profitable, diversified and lower-risk business than a typical biotech company.

Partner Program Technology Indication Development Stage
Pre-clinical/IND Phase 1 Phase 2 Phase 3/NDA Approved
Acrotech/CASI Evomela Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Alvogen Teriparatide Pelican Expression Technology Osteoporosis
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Alvogen Voriconazole Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Amgen/Ono Kyprolis Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Aziyo ECM portfolio ECM Med Device/Cardiology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Baxter Nexterone Captisol Cardiovascular Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Biocad Teberif Selexis SUREtechnology Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
CStone Sugemalimab OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Exelixis/Daiichi-Sankyo Minnebro Other/NCE Metabolic Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Gilead Veklury Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Gloria/Arcus Zimberelimab (AB122) OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Hikma Pharmaceuticals Voriconazole (EU) Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Jazz Pharmaceuticals RYLAZE™ Pelican Expression Technology Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Lundbeck Carnexiv Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Melinta Baxdela Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Merck Noxafil IV Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Merck VAXNEUVANCE™ Pelican Expression Technology Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Nanjing King-Friend Voriconazole (China and US) Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Par Pharmaceuticals Posaconazole-Par Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Pfizer Duavee Other/NCE Women's Health
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Pfizer VFEND Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Pfizer Viviant/Conbriza Other/NCE Women's Health
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Sage Zulresso Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Sedor Sesquient Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Serum Institute of India CRM197-Pneumosil Pelican Expression Technology Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Zydus Cadila Bryxta and Zybev Selexis SUREtechnology Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Zydus Cadila Exemptia Selexis SUREtechnology Inflammatory Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Zydus Cadila Vivitra Selexis SUREtechnology Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Zydus Cadila Vortuxi Selexis SUREtechnology Inflammatory Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA Complete
Approved In Progress
Aldeyra Reproxalap Captisol Ophthalmology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Biocad BCD-066 (Darbopoeitin) Selexis SUREtechnology Hematology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Genentech Tiragolumab OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
IBC Generium GNR-008 (Imiglugerase biosimilar) Selexis SUREtechnology Genetic Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Hanall Biopharma/Harbour BioMed/Immunovant Batoclimab OmniAb Autoimmune
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Janssen Teclistamab (JNJ-64007957) OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Marinus Ganaxolone-IV Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Novan SB206 Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Outlook Therapeutics ONS-5010 Selexis SUREtechnology Ophthalmology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Palvella Therapeutics PTX-022 Other/NCE To Be Determined
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Sage Zulresso (COVID-19) Captisol Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Sanofi Sutimlimab Captisol Autoimmune
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Serum Institute of India CRM197 Pelican Expression Technology Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Sunshine Lake Pharma Vilazodone Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Takeda Pevonedistat (TAK-924) Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Travere Therapeutics Sparsentan Other/NCE Metabolic Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Verona Ensifentrine Captisol Respiratory Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Xi'an Xintong Pradefovir HepDirect Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 Complete
Phase 3/NDA In Progress
Approved Not Started
Cantex CX-01 Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
CTI Biopharma Tosedostat Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Eisai FYCOMPA (Perampanel) Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Elevation Oncology Seribantumab Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Genmab GEN1046 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
J-Pharma JPH203-SBECD Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Merck CRM197 Pelican Expression Technology Infectious Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Merck KGaA M6620 Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Novartis ECF843 (Lubricin) Selexis SUREtechnology Ophthalmology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Opthea OPT-302 Selexis SUREtechnology Ophthalmology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Precision Biologics NPC-1C (Ensituximab) Selexis SUREtechnology Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Seelos Aplindore Other/NCE Central Nervous System
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Sermonix Lasofoxifene Other/NCE Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
VentiRx Motolimod (VTX-2337) Captisol Oncology
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Viking VK-0612 Other/NCE Metabolic Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Viking VK-5211 Other/NCE Musculoskeletal Disorder
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Viking VK-2809 HepDirect Metabolic Disease
Pre-clinical/IND Complete
Phase 1 Complete
Phase 2 In Progress
Phase 3/NDA Not Started
Approved Not Started
Amgen AMG-330 Captisol Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Apotex CE-Meloxicam Captisol Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Aptevo APVO436 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Exelixis ROR Captisol Inflammatory/Metabolic
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Gedeon Richter Bevacizumab biosimilar Selexis SUREtechnology Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Genekey Biotech SAL003 OmniAb Metabolic Disease
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Genmab GEN1047 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Janssen JNJ-67371244 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Janssen JNJ-70218902 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Janssen JNJ-78306358 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Jupiter Bioscience Viright Captisol Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
MEI ME-344 Captisol Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Merck KGaA M6223 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Phoenix Tissue Repair PTR-01 Selexis SUREtechnology Genetic Disease
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Protagonist Therapeutics PTG300 Captisol Hematology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Revision Therapeutics Rev0100 Captisol Ophthalmology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Servier S55746/S64315 Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Symphogen S095029 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Symphogen SYM022 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Symphogen SYM023 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Symphogen SYM024 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Takeda TAK-020 Captisol Inflammatory/Metabolic
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Takeda TAK-243 Captisol Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Takeda TAK-925 Captisol Central Nervous System
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Vaxxas Nanopatch Captisol To Be Determined
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
VentiRx VTX-1463 Captisol Inflammatory Disease
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Viking VK-0214 Other/NCE Genetic Disease
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Xi'an Xintong MB07133 HepDirect Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Teneobio TNB-383B OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Teneobio TNB-486 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started
Teneobio TNB-585 OmniAb Oncology
Pre-clinical/IND Complete
Phase 1 In Progress
Phase 2 Not Started
Phase 3/NDA Not Started
Approved Not Started


Ligand’s partners currently have over 100 drug candidates in discovery/pre-clinical development or an IND has been filed